With the boosted power of the new tube, Wittgenstein wakes up, miraculously regenerates the other smashed tubes connected to himself, and destroys the computer viruses within him, allowing him to be completely revived to as good as new. Knowing that they were given a final chance to save the animals, the appliances replaced the tube in the nick of time. Ratso then blames Radio, and guilt-ridden over condemning the animals to their doom at Tartarus Laboratories, Radio gives up his own tube which turns out to be the very rare tube they had been looking for, thus killing himself. Wittgenstein does his best with all his might, but the virus causes him to blow his remaining tube with a big explosion and apparently " is a goner". When they come back with the last apparent tube for miles, however, Radio and Ratso (after an argument with the tube) accidentally break it, and it seems that all hope is lost.
In an attempt to revive Wittgenstein to his superior state, Radio and Ratso go to the college's storage building to find the hard-to-find WFC 11-12-55 tube.
The appliances learn that unless they find a replacement quickly, Wittgenstein's tube will blow and lead to his apparent death. Carroll (WFC), and his birthdate, Novem(11-12-55). The name of the tube is a reference to the producer and screenwriter, Willard F. The miserable supercomputer reveals that he is living on one rare vacuum tube, named the "WFC 11-12-55".
When the appliances find Wittgenstein, they discover him abandoned, all alone and run-down and broken in the basement due to being infected by a computer virus, the same one that affected Rob's dorm room computer and the one in the vet clinic's lab when Wittgenstein try to contact them earlier. Meanwhile, in a dual plot of the film, Mack, Rob's lab assistant, plots to sell the injured animals Rob had been tending to as part of his courses to a place called "Tartaras Laboratories", the same place that Sebastian, an old monkey Rob is tending to, was sent to when he was just a baby. The appliances, along with the rat Ratso who found Wittgenstein, then seek to help Rob by finding Wittgenstein to reverse the effects of his computer virus, hence recovering the master's thesis. One night, while working on a thesis, his computer accidentally crashes due to being caused by a terrible computer virus from an old TLW-728 prototype supercomputer named Wittgenstein. Rob McGoarty, the owner of the appliances and whom they refer to as "The Master", is working in a veterinary clinic where he tends to injured animals. And is the sequel to Little Bear meets The Brave Little Toaster. Little Bear and The Brave Little Toaster to the Rescue is the second upcoming Little Bear/The Brave Little Toad crossover to be made by Hiatt Grey.